of Physiology 549 (Pt. 3): 945–952 (2003); J. M. Zeitzer et al., “Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression”, Journal of Physiology 526:3, 695–702 (2000).
522
J. A. Gastel, “Melatonin production: proteasomal proteolysis in serotonin N-acetyltransferase regulation”, Science 279, 1358–1360 (1998).
523
C. Dunlop and J. Cortazar in Los Autonautas de la Cosmopista o un Viage Atemporal (1983), quoted in Russell Foster and Leon Kreitzman, Rhythms of Life (London: Profile Books, 2004), 201.
524
S. Yamazaki et al., “Resetting central and peripheral circadian oscillators in transgenic rats”, Science 288, 682 (2000); интервью с Майклом Менакером, март 2005 года.
525
Kwangwook Cho, “Chronic ‘jet lag’ produces temporal lobe atrophy and spatial cognitive deficits”, Nature Neuroscience 4:6, 567–568 (2001); K. Cho et al., “Chronic jet lag produces cognitive deficits”, Journal of Neuroscience 20, RC66 (2000).
526
Bureau of Labor Statistics, “Workers on flexible and shift schedules in 2004 summary”, http://www.bls.gov/news.release/flex.nro.htm, retrieved October 16, 2006.
527
J. Arendt, “Shift-work: adapting to life in a new millennium”, presentation at the 2002 meeting of the Society for Sleep Research and Biological Rhythms, Amelia Island, Florida; интервью с Джозефиной Арендт, 21 марта 2005 года.
528
E. S. Schernhammer et al., “Rotating night shifts and risk of breast cancer in women participating in the Nurses’ Health Study”, Journal of the National Cancer Institute 93:20, 1563–1568 (2001); E. S. Schernhammer et al., “Night-shift work and risk of colorectal cancer in the Nurses’ Health Study”, Journal of the National Cancer Institute 95:11, 825–828 (2003).
529
T. Kubo et al., “Prospective cohort study of the risk of prostate cancer among rotating-shift workers: findings from the Japan collaborative cohort study”, American Journal of Epidemiology 164:6, 549–555 (2006).
530
L. Fu et al., “The circadian gene Period2 plays an important role in tumor suppression and DNA-damage response in vivo”, Cell 111, 41–50 (2002); M. Rosbash and J. S. Takahashi, “The cancer connection”, Nature 420, 373–374 (2002).
531
P. A. Wood et al., “Circadian clockBMAL-1 nuclear translocation gates WEE1 coordinating cell cycle progression, thymidylate synthase, and 5-fluorouracil therapeutic index”, Molecular Cancer Therapeutics 5:8, 2023–2033 (2006).
532
D. E. Blask et al., “Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats”, Cancer Research 65, 11174–11184 (2005).
533
Report of the President’s Commission on the Accident at the Three Mile Island (Washington, D. C.: U. S. Government Printing Office, 1979), http://www.pddoc.com/tmi2/kemeny/accident.htm.
534
M. A. Anderson, “Living in the shadow of Chernobyl”, Science 292, 420–421 (2001).
535
C. Czeisler, “Sleep: what happens when doctors do without it?”, Medical Center Hour, University of Virginia, March 1, 2006; Howard Markel, “The accidental addict”, New England Journal of Medicine 352, 966–968 (2005).
536
C. Landrigan et al., “Effect of reducing interns’ work hours on serious medical errors in intensive care units”, New England Journal of Medicine 351, 1838–1848 (2004).
537
Czeisler, “Sleep: what happens when doctors do without it?”.
538
N. Ayas et al., “Extended work duration and the risk of self-reported percutaneous injuries in interns”, Journal of the American Medical Association 296, 1055–1062 (2006).
539
J. K. Wyatt et al., “Circadian temperature and melatonin rhythms, sleep, and neurobehavioral function in humans living on a 20-h day”, American Journal of Physiology 277:4 (part 2), R1152–1163 (1999).
540
L. K. Barger et al., “Extended work shifts and the risk of motor vehicle crashes among interns”, New England Journal of Medicine 352, 125–134 (2005).
541
Интервью с Кристофером Ландриганом, октябрь 2006 года.
542
C. P. Landrigan et al., “Interns’ compliance with accreditation council for graduate medical education work-hour limits”, Journal of the American Medical Association 296: 9, 1063–1070 (2006).
543
J. K. Walsh, “Modafinil improves alertness, vigilance, and executive function during simulated night shifts”, Sleep 27:3, 434–439 (2004).
544
C. A. Czeisler et al., “Modafinil for excessive sleepiness associated with shift-work sleep disorder”, New England Journal of Medicine 353:5, 476–486 (2005).
545
Dement and Vaughan, The Promise of Sleep, 107; Foster and Kreitzman, Rhythms of Life, 12; Michael Smolensky and Lynne Lamberg, The Body Clock Guide to Better Health (New York: Holt, 2000), 133.
546
Foster and Kreitzman, Rhythms of Life, 12.
547
M. Takamoto et al., “An optical lattice clock”, Nature 435, 321–324 (2005).
548
Letter to Gerald Brennan, December 25, 1922, in Nigel Nicolson and Joanne Trautmann, eds., The Letters of Virginia Woolf, vol. 2 (New York: Harcourt, 1976), 598.
549
L. Shearman et al., “Interacting molecular loops in the mammalian circadian clock”, Science 288, 1013–1019 (2000).
